IL5RA HEK293
CBP74676
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| I. Background | |
| IL5RA（白细胞介素-5受体α亚基）是IL-5特异性受体的配体结合亚基，由IL5RA基因编码。它本身以较低亲和力结合IL-5，必须与共享的信号转导β亚基（βc/CD131）形成异二聚体，才能构成高亲和力功能性受体并启动下游信号。该受体在嗜酸性粒细胞的存活、分化和趋化中发挥关键作用，是哮喘和嗜酸性粒细胞相关疾病的重要治疗靶点。 | |
| II. Description | |
| IL5RA HEK293细胞，在 HEK293细胞的基础上，稳定表达 IL5RA。 | |
| III. Introduction | |
| Expressed gene: | IL5RA |
| Host Cell: | HEK293 |
| Stability: | 32 passages (in-house test, that not means the cell line will be instable beyond the passages we tested.) |
| Freeze Medium: | 90% FBS+10% DMSO |
| Culture Medium: | DMEM+10%FBS+2 μg/ml Puromycin |
| Mycoplasma Testing: | Negative |
| Storage: | Liquid nitrogen |
| Application(s): | Binding Assay,FACS |
| IV. Representative Data | |
 Figure 1. Recombinant IL5RA HEK293 constitutively expressing IL5RA. |
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